INDOLYLACETIC DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
The present invention relates to indolylacetic derivatives of Formula (I) for use in the treatment of neurodegenerative diseases, preferably Amyotrophic Lateral Sclerosis (ALS). The invention further relates to pharmaceutical compositions containing the same, as well as a process for obtaining the indolylacetic derivatives.
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice
Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, and Giuseppe Pignataro*
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